CHAPTER 1 - SKIN REJUVENATION

The Goal Of Rejuvenation
What Are The Features Of Healthy Skin?
What Are The Benefits Of Healthy Skin?
What Can We Do To Optimize Skin Health?
What Are The Key Goals Of Ideal Skin Rejuvenation?
Regulating Cell Function
Regulating Keratinocyte Function
Regulating Melanocyte Function
Regulating Fibroblast Function
Features Of Ablative And Non-Ablative Treatments

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CHAPTER 2 - CELL FUNCTION

Regulating Cell Function To Optimize Skin Health
What Nutrients Are Essential For Regulating Cell Function?
Epidermal Cell Requirements For Optimal Function
Lipid Peroxidation
Melanogenesis
Product Ingredients Affecting Melanogenesis For Use Post-Needling
Fibroblasts
Vitamin C And Collagen Formation
Vitamin C And Other Functions
Vitamin A And Collagen Formation
How Does Vitamin A Result In Collagen Formation?
The Vitamin A Story
Retinoic Acid
Vitamin A And Other Functions
Key Amino Acids For Collagen Synthesis: Proline And Lysine
Copper Peptides For Collagen Synthesis
Other Peptides That Target Collagen Synthesis
Zinc, A Co-Factor In Collagen Synthesis
Zinc Fingers
Bioflavonoids For Collagen Synthesis
Pycnogenol™
Grape Seed Extract (Vitis Vinefera)
Green Tea Extract (Camellia Sinensis)
Stem Cells
Hormones
Iron As A Co-Factor
Silicone, Magnesium, Selenium And Calcium
Glucosamine
Alpha Linolenic & Linoleic Acid (Omega 3 & 6)
What Growth Factors Regulate Cell Function?
Cellular Communication Via Growth Factors And Cytokines

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CHAPTER 3 - WOUND HEALING

Scarless Wound Healing (Embryo Model)
Distinctive Cellular And Molecular Features Of Embryo Wound Healing
Differences Between Wound Healing In Embryos And Adults
Other Differences And Potential Influences Unique To Embryonic Wound Healing
The Adult Wound Healing Process
The Phases Of Wound Healing
Coagulation Phase
Inflammatory Phase
Proliferative Phase
Lag Phase
Fibroplastic Phase
Maturative And Remodeling Phase
Plausible Explanations For The Differences Between The Embryo And Adult Wound Healing Models
Growth Factors
The Role Of Hyaluronic Acid
Why Does Fibrosis Result With IPL, Laser, Fraxel, Thermage Etc.?
Conclusions And Significance
The Role Of Key Cells And The Phases Of Wound Healing (Biochemistry)
Time Line Diagram

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CHAPTER 4 - DERMAL NEEDLING - WHAT IT IS AND WHAT IT CAN DO

History And Background Of Percutaneous Collagen Induction Therapy
The Early Stage
Subcision
Advanced Needle Abrasion
Development Of Advanced Needle Devices
Cosmetic Versus Medical Needling
Cosmetic Needling
How Does It Work?
Effects On The Epidermis
Effects On The Dermis
Medical Needling
How Does It Work?
What Are The Most Effective Uses For Dermal Rolling?
How Needling Improves Various Skin Disorders & Conditions:
Lax Skin & Wrinkles
Pathophysiology: What Went Wrong?
What Are Some Of The Causes Of Loss Of Structural Integrity?
How Does Needling Correct Loss Of Structural Integrity?
UV Damage (Actinic Keratosis & Non-Melanoma Skin Cancers (NSC’s)
Pathophysiology: What Went Wrong?
What Are Some Of The Causes For This Failed Repair Or Destruction/Removal?
How Does Needling Correct UV Damage?
Hyperpigmentation
Pathophysiology: What Went Wrong?
Overstimulation Of These Signaling Systems
Damaged Infrastructure
What Are Some Of The Causes For Hyperpigmentation?
How Does Needling Correct Hyperpigmentation?
Scars
Pathophysiology: What Went Wrong?
Keloids
Hypertrophic Scars
What Are Some Of The Causes For This?
How Does Needling Correct Scars?
Stretch Marks (Striae Distensae)
Pathophysiology: What Went Wrong?
Histological Findings
What Are Some Of The Causes For Stretch Marks?
How Does Needling Correct Stretch Marks?
Rosacea
Pathophysiology: What Went Wrong?
What Are Some Of The Aggravating Factors Of This Condition?
How Does Needling Correct Rosacea?
Hair Loss
Pathophysiology: What Went Wrong?
Androgenetic Alopecia
Alopecia Areata
What Are Some Of The Causes Of Hair Loss?
How Does Needling Correct Hair Loss?
Synergistic Products

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CHAPTER 5 - TREATMENT PARAMETERS 
AND PROTOCOLS FOR NEEDLING

Consultation & Treatment Records
Contra-Indications/Special Precautions
Atopy, Asthma, Hay Fever And Allergies
Rosacea
Anti-Coagulated Patients
Drugs And Supplements Associated With Photosensitivity
Considerations With Fitzpatrick III and Up
The Collagenase Story
Prolonging The Inflammatory Phase
Safety With Botox And Fillers
IPL, Laser, Fraxel etc.
Pregnancy
Keloid
Immune Suppressed Patients
Diabetes
Parabens
Skin Preparation – Home
Home Care Products
Cosmetic Rolling At Home
Cosmetic Roller Instructions
Skin Preparation - Clinic
Topical Anesthesia vs. Dental Blocks
What Size Roller?
Clinical Techniques
Medical Needling Protocol
Preparation
How To Roll
Procedure
Best Practice Rolling Technique
End Point
Adjuncts: Platelet Therapy
How To Clean The Roller
Post Treatment Considerations
Immediate Post Treatment Care
Need For Valtrex
Home Care Considerations
Post 0.5 mm, 1.0 mm and 2.0 mm Treatment Care (Medical Needling)
Predicted Appearance After Medical Needling
Post Treatment Plan Guideline
Frequency And Required Number Of Treatments

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CHAPTER 6 - CASE STUDIES

Expectations And Outcomes
Wrinkles
UV Damage
Lax Skin
Actinic Keratosis
Hyperpigmentation
Scars
Stretch Marks
Hair Loss
Adverse Reactions
Case Study
Conclusion And Recommendations

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CHAPTER 7 - OVERVIEW OF TREATMENT MODALITIES

Synergistic Treatment Programs
The Concept Of Corneotherapy - Back To The Future
Non-Ablative Treatments
Light-Emitting Diode (LED)
Sonophoresis/Iontophoresis
Lymph Drainage
Intense Pulse Light (IPL)
Mid-Infrared Lasers
Nd:YAG -1064-1320 nm
Fraxel – 1530 nm
Ablative Treatments
Chemical Peels
Alpha Hydroxy Acids (AHA)
Glycolic
Lactic Acid
Mandelic Acid
Beta Hydroxy Acids (BHA)
Salicylic Acid
Beta-Lipohydroxy Acid (C8-Lipohydroxy Acid) (LHA)
Other Acids
Trichloroacetic Acid (TCA)
Enzymes
Bromelain Or Papaine
Microdermabrasion (MDA)
Laser Resurfacing (Ablative)
Pulsed Dye Laser
Infrared Lasers
Other Modalities
Hyperbaric Oxygen Therapy
Radio-Frequency
Summary Of Synergistic Treatments

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CHAPTER 8 - ADVANTAGES AND DISADVANTAGES OF NEEDLING

Conclusion
Frequently Asked Questions
Abbreviation Notes
References

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